Antimicrobial Stewardship & Patient Safety
"Antibiotic resistance is one of the biggest public health challenges of our time. Each year in the U.S., at least 2.8 million people get an antibiotic-resistant infection, and more than 35,000 people die. Fighting this threat is a public health priority that requires a collaborative global approach across sectors."
Photograph/Illustration: Generated with AI
Antimicrobial stewardship is a coordinated, evidence-based approach to using antibiotics and other antimicrobial drugs in the most effective, responsible way. Its core purpose is to slow the spread of antimicrobial resistance while still ensuring that patients get the treatment they need. Here, we bring you news and insights about developments in the field.
What AMS focuses on
- Using the right drug, at the right dose, for the right duration. This avoids both under-treating infections and overusing antibiotics.
- Preventing unnecessary prescriptions. Many infections - especially viral ones - don’t benefit from antibiotics at all.
- Monitoring resistance patterns. Hospitals and health systems track which bacteria are becoming harder to treat.
- Improving diagnostics. Faster, more accurate tests help clinicians choose targeted treatments instead of broad-spectrum antibiotics.
- Stewardship and Surveillance: techniques and practices that monitor resistance patterns and track infection outbreaks support antimicrobial stewardship programs, helping healthcare providers make informed decisions and slow the spread of AMR.
News
View allRecord High': 146 Experts Call to Declare Climate Change a Global Health Emergency
Abstract
As record heat interrupts work, overloads hospitals, and claims thousands of lives around the world, international experts are calling for climate change to be officially recognized as a global health emergency, in The Lancet's 2026 Countdown on Health and Climate Change. The rate of increase in many climate-related health threats is accelerating, while heat deaths linked to climate change have reached a record-high, and the economic toll is battering vulnerable sectors and communities the hardest," says climate health researcher Marina Romanello, executive director of The Lancet Countdown. They say the World Health Organization and United Nations must declare climate change a global health emergency, coordinate governments to put human health at the center of climate decisions, and increase grant-based funding to finance climate and health initiatives. "Ten years ago, we proposed that responding to climate change could offer the greatest health opportunity of the 21st century through adaptation efforts and rapid progress in phasing down fossil fuels and other emission sources", says global health expert and The Lancet Countdown co-chair Anthony Costello."Var sjunde flygresenär hade antibiotika i bagaget
Abstract
Andelen varierade ganska mycket mellan flygplatserna, på Arlanda hade 23 procent av de kontrollerade resenärerna antibiotika med sig, att jämföra med 10 procent på både Landvetter och Gardermoen. Av de som anlände från EU- och EES-länder hade bara 3 procent antibiotika med sig, jämfört med 27 procent bland resenärer från Asien. – Man kan i alla fall inte säga att det här inte är ett problem, utan det är något man behöver titta närmare på, säger Anna Moberg, universitetslektor vid Linköpings universitet och ansvarig för studien, i ett pressmeddelande. Resultaten kan därför egentligen inte användas för att uppskatta hur stor andel av alla flygresenärer som för in antibiotika.AI drug discovery is changing which experiments reach patients
Abstract
A designed molecule reaches a clinical test Rentosertib offers a concrete example of the journey. The highest daily dose group showed a mean increase in forced vital capacity of 98.4 millilitres, compared with a decline of 20.3 millilitres on placebo. This was a repurposing hypothesis for an established drug, not the invention of a new molecule. The strongest commercial proposition is consequently specific: a better target decision, a more informative experiment or a workable referral.Factors Tied to Lower Risk for Ventilator-Associated Pneumonia
Abstract
Female sex, a non-neurologic diagnosis at admission, and antibiotics given during the first 2 days of ventilation were each linked to a lower risk for VAP. Researchers conducted a prospective cohort study across eight ICUs in Northern Italy from 2021 to 2024 to estimate the 15‑day incidence of VAP and to identify clinical and pharmacologic factors associated with its occurrence among patients intubated for non‑pulmonary indications. The primary outcome was the time to the first VAP episode during the first 15 days of ventilation. Overall, 148 patients (36.5%) developed VAP within 15 days, the median time to onset was day 6, and the overall incidence rate was 43.2 per 1000 ventilator‑days at risk.33-årig mand anholdt i sag om salg af ulovlig medicin
Abstract
Manden er sigtet for salg af ulovlig medicin via en hjemmeside og på sociale medier. Ved en aktion i Køge mandag har National enhed for Særlig Kriminalitet (NSK) anholdt og sigtet en 33-årig mand for salg af ulovlig medicin. Under den indledende efterforskning har NSK afdækket, at emballagen kan kædes sammen med en hjemmeside, som den 33-årige ejer og betaler for, og som udbyder lægemidler online. Det er meget farligt at købe medicin på det illegale marked, da man ingen sikkerhed har for, hvad der er puttet i produkterne.
